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Cat. No.: HY-50898BR

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Lapatinib ditosylate monohydrate (Standard)

Name: Lapatinib ditosylate monohydrate (Standard)
Brand: MedChemExpress
SKU: HY-50898BR
Price: 38.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: GW572016 ditosylate monohydrate (Standard); GW2016 ditosylate monohydrate (Standard))

Customer Review

Based on 1 Customer Validation

Lapatinib (ditosylate monohydrate) (Standard) is the analytical standard of Lapatinib (ditosylate monohydrate). This product is intended for research and analytical applications. Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.

For research use only. We do not sell to patients.

Purity : 98.15%
CAS No.: 388082-78-8
Formula: C₄₃H₄₄ClFN₄O₁₁S₃
Molecular Weight:943.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Lapatinib ditosylate monohydrate (Standard) Chemical Structure

CAS No.: 388082-78-8

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Antibody-Drug Conjugates

One-stop solution for XDC (ADC/PDC/RDC/ApDC/FDC/ISAC/VDC/SMDC)

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 388082-78-8
Appearance Solid
Molecular Weight 943.48
Formula C₄₃H₄₄ClFN₄O₁₁S₃
Color Light yellow to yellow
SMILES

O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OCC5=CC=CC(F)=C5)C(Cl)=C4)N=CN=C3C=C2)O1)(C)=O.O=S(C6=CC=C(C)C=C6)(O)=O.O=S(C7=CC=C(C)C=C7)(O)=O.O
Synonyms

GW572016 ditosylate monohydrate (Standard); GW2016 ditosylate monohydrate (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
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- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Rusnak DW, et al. The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo. Mol Cancer Ther. 2001 Dec;1(2):85-94. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Lapatinib ditosylate monohydrate (Standard)

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Lapatinib ditosylate monohydrate (Standard)

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