Laventatug
Based on 1 Customer Validation
Laventatug (BRY-812 Antibody) is a humanized IgG1-kappa monoclonal antibody targeting hSLC39A6. Laventatug serves as the antibody component for the synthesis of the ADC molecule BRY-812 and exhibits anti-tumor activity.
For research use only. We do not sell to patients.
- Purity : 95.534%
- CAS No.: 3009829-91-5
- Molecular Weight:146.818 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
[1]|
SLC39A6/ZIP6 |
In Vitro
BRY812 is an ADC targeting SLC39A6 that significantly inhibits the growth, stemness, and metastasis of colorectal cancer cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized LIV-1/SLC39A6 Protein, Human (HEK293, His, HY-P78749) can bind Laventatug. The EC50 for this effect is 11.09 ng/mL.
Chemical Information
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CAS No. 3009829-91-5
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Appearance Liquid
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Molecular Weight 146.818 kDa
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Color Colorless to light yellow
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SMILES
N/A
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Synonyms
BRY-812 Antibody
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)