LDH-IN-6
LDH-IN-6 is a dehydrogenase inhibitor with an I50 of 69 µM against lactate dehydrogenase (LDH). LDH-IN-6 also inhibits glyceraldehyde phosphate dehydrogenase (GPDH) (I50 300 µM), glutamate dehydrogenase (Glu-DH) (I50 400 μM), and malate dehydrogenase (MDH) (I50 500 μM). LDH-IN-6 is useful for research on dehydrogenase-related diseases and can also serve as an intermediate for research related to organic synthesis.
For research use only. We do not sell to patients.
- CAS No.: 35975-82-7
- Formula: C18H16N2O4
- Molecular Weight:324.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
LDH-IN-6 is obtained by reduction of precursor compound 27 under acidic conditions; it can also be converted into candidate irreversible inhibitors of 4 dehydrogenases via acylation with suitable derivatives of PhSO2F[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 35975-82-7
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Molecular Weight 324.33
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Formula C18H16N2O4
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SMILES
O=C(C1=CN(CC2=CC(N)=CC=C2)C3=CC=C(C=C3C1=O)OC)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LDH-IN-6 Related Classifications
HY-189037 Related Classifications
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