LP-003
LP-003 is an anti-IgE antibody that binds free human IgE with a Kd of 2.08 pM. LP-003 blocks the interaction of IgE with FcεRI and CD23, thereby preventing IgE-mediated signaling. LP-003 binds FcRn at acidic pH, reducing clearance and prolonging exposure. LP-003 inhibits IgE-mediated reporter gene expression. LP-003 can be used for research on seasonal allergic rhinitis.
For research use only. We do not sell to patients.
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Species Reactivity
Human
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Target
IgE
Conjugated
Unconjugated
Application
ELISA, FACS, Functional assay
Chemical Information
-
SMILES
[LP-003]
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)