Lysophosphatidylcholine C19:0
Based on 1 Customer Validation
Lysophosphatidylcholine C19:0 (19:0 Lyso PC) is a lysophosphatidylcholine with a fully saturated C19 acyl chain. When combined with LPS (HY-D1056), Lysophosphatidylcholine C19:0 induces the secretion of IL-1β by human monocyte-derived dendritic cells. Lysophosphatidylcholine C19:0 reduces the viability of monocyte-derived dendritic cells.
For research use only. We do not sell to patients.
- Purity : 99.0%
- CAS No.: 108273-88-7
- Formula: C27H56NO7P
- Molecular Weight:537.71
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
Lysophosphatidylcholine C19:0 (1.3-82.5 μM; 2 days) stimulates human monocyte-derived dendritic cells to secrete IL-1β in a concentration-dependent manner, with an activity index of 6.34 activity units, but causes dose-dependent reduction in cell viability[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 108273-88-7
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Appearance Solid
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Molecular Weight 537.71
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Formula C27H56NO7P
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
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Synonyms
1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; 19:0 Lyso PC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (263 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Lysophosphatidylcholine C19:0
- 108273-88-7
- 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
- 19:0 Lyso PC
- Liposome
- Interleukin Related
- human PBMCs
- B16-F10 melanoma-bearing mice
- non-human primate moDCs
- Th17 memory CD4+ T cells
- murine BMDCs
- Th1 memory CD4+ T cells
- IL-1β
- canine PBMCs
- LPS
- human monocyte-derived dendritic cells
- Inhibitor
- inhibitor
- inhibit