Malabaric acid
Malabaric acid is a cyclooxygenase inhibitor that inhibits COX-1 (IC50 = 11.5 µM) and COX-2 (IC50 = 46.9 µM). Malabaric acid inhibits lipid peroxidation and can be used in antioxidant research.
For research use only. We do not sell to patients.
- CAS No.: 67910-87-6
- Formula: C20H30O2
- Molecular Weight:302.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
COX-1 11.5 μM (IC50) |
COX-2 46.9 μM (IC50) |
In Vitro
Malabaric acid (10.3-164.8 µM; 21 min) inhibits lipid peroxidation in a liposome-based LPO assay, with an IC50 of 100.3 µM[1].
Malabaric acid (41.2-329.6 µM; 24 h) exhibits moderate MTT-reducing antioxidant activity in a cell-free MTT assay, with an IC50 of 192 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 67910-87-6
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Molecular Weight 302.45
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Formula C20H30O2
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SMILES
O=C(/C1=C\CC/C(C)=C/C[C@H](C(C)=C)CC/C(C)=C/CC1)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Malabaric acid Related Classifications
HY-N22072 Related Classifications
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