meso-Erythritol-d6
Based on 1 Customer Validation
meso-Erythritol-d6 is the deuterium labeled meso-Erythritol (HY-100551). meso-Erythritol is a sugar alcohol that found in a variety of foods (e.g., pear, watermelon), is 60-80% as sweet as sucrose, and can be used as low-calorie sweetener food additives.
For research use only. We do not sell to patients.
- Purity : 99.9%
- CAS No.: 2714435-98-8
- Formula: C4H4D6O4
- Molecular Weight:128.16
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2714435-98-8
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Unlabeled CAS 149-32-6
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Appearance Solid
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Molecular Weight 128.16
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Formula C4H4D6O4
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Color White to off-white
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SMILES
OC([2H])([2H])[C@@](O)([2H])[C@]([2H])(O)C([2H])([2H])O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (780.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Hootman KC, et al. Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults. Proc Natl Acad Sci U S A. 2017 May 23;114(21):E4233-E4240. [Content Brief]
[3]. Fujii K, et al. Physical characterization of meso-erythritol as a crystalline bulking agent for freeze-dried formulations. Chem Pharm Bull (Tokyo). 2015;63(5):311-7. [Content Brief]
[4]. Sreenath K, et al. Analysis of erythritol in foods by polyclonal antibody-based indirect competitive ELISA. Anal Bioanal Chem. 2008 May;391(2):609-15. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.8027 mL | 39.0137 mL | 78.0275 mL | 195.0687 mL |
| 5 mM | 1.5605 mL | 7.8027 mL | 15.6055 mL | 39.0137 mL | |
| 10 mM | 0.7803 mL | 3.9014 mL | 7.8027 mL | 19.5069 mL | |
| 15 mM | 0.5202 mL | 2.6009 mL | 5.2018 mL | 13.0046 mL | |
| 20 mM | 0.3901 mL | 1.9507 mL | 3.9014 mL | 9.7534 mL | |
| 25 mM | 0.3121 mL | 1.5605 mL | 3.1211 mL | 7.8027 mL | |
| 30 mM | 0.2601 mL | 1.3005 mL | 2.6009 mL | 6.5023 mL | |
| 40 mM | 0.1951 mL | 0.9753 mL | 1.9507 mL | 4.8767 mL | |
| 50 mM | 0.1561 mL | 0.7803 mL | 1.5605 mL | 3.9014 mL | |
| 60 mM | 0.1300 mL | 0.6502 mL | 1.3005 mL | 3.2511 mL | |
| 80 mM | 0.0975 mL | 0.4877 mL | 0.9753 mL | 2.4384 mL | |
| 100 mM | 0.0780 mL | 0.3901 mL | 0.7803 mL | 1.9507 mL |