MG-Lin3
MG-Lin3 is a Lin28 molecular glue degrader. MG-Lin3 recruits the E3 ubiquitin ligase RNF126 to form a ternary complex, induces the degradation of Lin28 via the ubiquitin-proteasome pathway, and restores the levels of mature let-7 miRNA. MG-Lin3 can be used in research on ovarian cancer, ovarian teratocarcinoma, and uterine cancer.
For research use only. We do not sell to patients.
- Formula: C30H30N6O4
- Molecular Weight:538.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 538.60
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Formula C30H30N6O4
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SMILES
COC1=CC=C(C=C1)C(/C=C/C(N2CCC(CC2)C(N(C3=CC=CC(C4=NN5C(C)=NN=C5C=C4)=C3)C)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)