MGL-IN-4
MGL-IN-4 (compound 16) is a covalent monoacylglycerol lipase (MGL) inhibitor with an IC50 of 7.8 nM against hMGL. MGL-IN-4 covalently modifies a key cysteine residue of MGL through ring-opening release of an active sulfur atom, locking the lid domain in a closed conformation to allosterically inhibit its activity. MGL-IN-4 can be used in studies of neuroprotection and anti-inflammation.
For research use only. We do not sell to patients.
- CAS No.: 64552-26-7
- Formula: C9H8N2O2S
- Molecular Weight:208.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
hMGL 7.8 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 64552-26-7
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Molecular Weight 208.24
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Formula C9H8N2O2S
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SMILES
O=C(N)CN1SC2=CC=CC=C2C1=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MGL-IN-4 Related Classifications
HY-189484 Related Classifications
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