MMA-NODAGA TFA
Based on 1 Customer Validation
MMA-NODAGA TFA is a chelator for site-specific labeling of targeting proteins containing unpaired cysteine. MMA-NODAGA TFA can be used to conjugate with exosome and 64Cu in image with positron emission tomography (PET).
For research use only. We do not sell to patients.
- Purity : 98.02%
- Formula: C23H32F3N5O11
- Molecular Weight:611.52
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
Description
Chemical Information
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Appearance Oil
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Molecular Weight 611.52
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Formula C23H32F3N5O11
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Color White to off-white
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SMILES
O=C(O)C(F)(F)F.O=C(CN1CCN(CCN(C(CCC(NCCN2C(C=CC2=O)=O)=O)C(O)=O)CC1)CC(O)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (163.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Sara F F Almeida , et al. Osteosarcoma-Derived Exosomes as Potential PET Imaging Nanocarriers for Lung Metastasis. Small. 2022 Dec;18(49):e2203999. [Content Brief]
[2]. Mohamed Altai, et al. Influence of nuclides and chelators on imaging using affibody molecules: comparative evaluation of recombinant affibody molecules site-specifically labeled with ⁶⁸Ga and ¹¹¹In via maleimido derivatives of DOTA and NODAGA. Bioconjug Chem. 2013 Jun 19;24(6):1102-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6353 mL | 8.1763 mL | 16.3527 mL | 40.8817 mL |
| 5 mM | 0.3271 mL | 1.6353 mL | 3.2705 mL | 8.1763 mL | |
| 10 mM | 0.1635 mL | 0.8176 mL | 1.6353 mL | 4.0882 mL | |
| 15 mM | 0.1090 mL | 0.5451 mL | 1.0902 mL | 2.7254 mL | |
| 20 mM | 0.0818 mL | 0.4088 mL | 0.8176 mL | 2.0441 mL | |
| 25 mM | 0.0654 mL | 0.3271 mL | 0.6541 mL | 1.6353 mL | |
| 30 mM | 0.0545 mL | 0.2725 mL | 0.5451 mL | 1.3627 mL | |
| 40 mM | 0.0409 mL | 0.2044 mL | 0.4088 mL | 1.0220 mL | |
| 50 mM | 0.0327 mL | 0.1635 mL | 0.3271 mL | 0.8176 mL | |
| 60 mM | 0.0273 mL | 0.1363 mL | 0.2725 mL | 0.6814 mL | |
| 80 mM | 0.0204 mL | 0.1022 mL | 0.2044 mL | 0.5110 mL | |
| 100 mM | 0.0164 mL | 0.0818 mL | 0.1635 mL | 0.4088 mL |