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Cat. No.: HY-W701876

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Monocyclohexyl phthalate

Name: Monocyclohexyl phthalate
Brand: MedChemExpress
SKU: HY-W701876
Price: 70.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Monocyclohexyl phthalate is a phthalate metabolite and a competitive UGT1A9 inhibitor with an IC₅₀ of 3.29 μM and a K_i of 0.09 μM. Monocyclohexyl phthalate can be used in research on impaired sperm quality and birth weight.

For research use only. We do not sell to patients.

CAS No.: 7517-36-4
Formula: C₁₄H₁₆O₄
Molecular Weight:248.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Monocyclohexyl phthalate Chemical Structure

CAS No.: 7517-36-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

IC₅₀ & Target

^[1]

UGT1A9

3.29 μM (IC₅₀)

In Vitro

Monocyclohexyl phthalate (0-100 μM; 30 min) competitively inhibits recombinant human UGT1A9-catalyzed 4-MU glucuronidation with an IC₅₀ of 3.29 μM and a K_i of 0.09 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 7517-36-4
Molecular Weight 248.28
Formula C₁₄H₁₆O₄
SMILES

O=C(O)C=1C=CC=CC1C(=O)OC2CCCCC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Du Z, et al. Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters. Chemosphere. 2018 Apr;197:7-13. [Content Brief]

[2]. Vrachnis N, et al. Phthalates and fetal growth velocity: tracking down the suspected links. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2022 Dec;35(25):4985-4993.

[3]. Duty SM, et al. The relationship between environmental exposures to phthalates and DNA damage in human sperm using the neutral comet assay. Environmental health perspectives. 2003 Jul;111(9):1164-9.

[4]. Duty SM, et al. Phthalate exposure and human semen parameters. Epidemiology (Cambridge, Mass.). 2003 May;14(3):269-77.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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