Niclosamide olamine (Standard)
Niclosamide olamine (Standard) (BAY2353 olamine (Standard)) is the analytical standard of Niclosamide olamine (HY-B0497C). This product is intended for research and analytical applications. Niclosamide (BAY2353) olamine is an orally active antihelminthic agent used in parasitic infection research. Niclosamide olamin is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide olamin has biological activities against cancer, and inhibits DNA replication in Vero E6 cells.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 1420-04-8
- Formula: C15H15Cl2N3O5
- Molecular Weight:388.20
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
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HY-B0497
NiclosamideAntihelminthic Agent -
HY-B0497C
Niclosamide olamineAntihelminthic Agent -
HY-B0497R
Niclosamide (Standard)Antihelminthic Agent -
HY-B0497G
Niclosamide (GMP)Antihelminthic Agent -
HY-B0069
FludarabineDNA Synthesis Inhibitor -
HY-17504
Rosuvastatin CalciumHMGCR Inhibitor -
HY-13818
StatticSTAT3 Inhibitor -
HY-B0167
Salicylic acidCOX-2 Inhibitor -
HY-B1436
NifuroxazideBacterial Inhibitor -
HY-17504R
Rosuvastatin Calcium (Standard) -
HY-100753
STAT3-IN-1STAT3 Inhibitor -
HY-18980
RottlerinPKC Inhibitor
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1420-04-8
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Molecular Weight 388.20
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Formula C15H15Cl2N3O5
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SMILES
O=C(NC1=CC=C([N+]([O-])=O)C=C1Cl)C2=CC(Cl)=CC=C2O.NCCO
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Synonyms
BAY2353 olamine (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. P Andrews, et al. The biology and toxicology of molluscicides, Bayluscide. Pharmacol Ther. 1982;19(2):245-95. [Content Brief]
[2]. Wei Chen, et al. Niclosamide: Beyond an antihelminthic drug. Cell Signal. 2018 Jan;41:89-96. [Content Brief]
[3]. Kei Satoh, et al. Identification of Niclosamide as a Novel Anticancer Agent for Adrenocortical Carcinoma. Clin Cancer Res. 2016 Jul 15;22(14):3458-66. [Content Brief]
[4]. Xiaomei Ren, et al. Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway. ACS Med Chem Lett. 2010 Sep 7;1(9):454-9. [Content Brief]
[5]. Chang-Jer Wu, et al. Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide. Antimicrob Agents Chemother. 2004 Jul;48(7):2693-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Niclosamide olamine (Standard) Related Classifications
HY-B0497CR Related Classifications
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