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Cat. No.: HY-186378

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NLRP3-IN-101

NLRP3-IN-101 is a NLRP3 inhibitor. NLRP3-IN-101 can be used for research on inflammatory diseases.

For research use only. We do not sell to patients.

CAS No.: 2411530-87-3
Formula: C₂₉H₃₆N₄O₆S
Molecular Weight:568.68

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

NLRP3-IN-101 Chemical Structure

CAS No.: 2411530-87-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

NLRP3-IN-101 is a NLRP3 inhibitor. NLRP3-IN-101 can be used for research on inflammatory diseases^[1].

IC₅₀ & Target

^[1]

NLRP3

All NOD-like Receptor (NLR) Isoforms :

In Vitro

Adaptive Immunity

NLRP3-IN-101 (Compound 45) (3 h) inhibits NLRP3 in both THP-i cells and human whole blood (HWB), with IC₅₀ values of ≤0.25 μM and ≤1 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2411530-87-3
Molecular Weight 568.68
Formula C₂₉H₃₆N₄O₆S
SMILES

O=C(NC1=C(C2=CC(OC3CCN(C)CC3)=NC=C2)C(C)=CC4=C1CCC4)NS(=O)(C5=CC(C(C)(O)C)=CO5)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Angus Macleod, et al. Novel sulfoneurea compounds. WO2020035466A1. WIPO (PCT). 2018-08-15.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
References

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NLRP3-IN-101

All NOD-like Receptor (NLR) Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

NLRP3-IN-101 Related Classifications

HY-186378 Related Classifications

Bioz

Keywords

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