NSD2 ligand 2
Based on 1 Customer Validation
NSD2 ligand 2 is a ligand for target protein for PROTAC that specifically binds to NSD2. NSD2 ligand 2 can be used to synthesize PROTAC MS159 (HY-151101).
For research use only. We do not sell to patients.
- Purity : 98.92%
- CAS No.: 3031353-62-2
- Formula: C28H29N5O5
- Molecular Weight:515.56
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Histone Methyltransferase Isoforms
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Biological Activity
Description
IC50 & Target
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NSD2 |
In Vitro
The ligand of the target protein will cause PROTAC to attach to the target protein for ubiquitination and subsequent degradation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3031353-62-2
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Appearance Solid
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Molecular Weight 515.56
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Formula C28H29N5O5
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Color White to light yellow
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SMILES
NCCCOC1=CN=C(C=C1)NC(C2=CC=C(C=C2)CN(C3CC3)C(C4=CC=C5NC(COC5=C4)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (193.96 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.9396 mL | 9.6982 mL | 19.3964 mL | 48.4910 mL |
| 5 mM | 0.3879 mL | 1.9396 mL | 3.8793 mL | 9.6982 mL | |
| 10 mM | 0.1940 mL | 0.9698 mL | 1.9396 mL | 4.8491 mL | |
| 15 mM | 0.1293 mL | 0.6465 mL | 1.2931 mL | 3.2327 mL | |
| 20 mM | 0.0970 mL | 0.4849 mL | 0.9698 mL | 2.4245 mL | |
| 25 mM | 0.0776 mL | 0.3879 mL | 0.7759 mL | 1.9396 mL | |
| 30 mM | 0.0647 mL | 0.3233 mL | 0.6465 mL | 1.6164 mL | |
| 40 mM | 0.0485 mL | 0.2425 mL | 0.4849 mL | 1.2123 mL | |
| 50 mM | 0.0388 mL | 0.1940 mL | 0.3879 mL | 0.9698 mL | |
| 60 mM | 0.0323 mL | 0.1616 mL | 0.3233 mL | 0.8082 mL | |
| 80 mM | 0.0242 mL | 0.1212 mL | 0.2425 mL | 0.6061 mL | |
| 100 mM | 0.0194 mL | 0.0970 mL | 0.1940 mL | 0.4849 mL |
NSD2 ligand 2 Related Classifications
HY-48149 Related Classifications
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