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Cat. No.: HY-N8425

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Octacosanoic acid

Name: Octacosanoic acid
Brand: MedChemExpress
SKU: HY-N8425
Price: 50.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Montanic acid)

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Based on 1 Customer Validation

Octacosanoic acid (Montanic acid) is a long-chain saturated fatty acid and a major component of sugarcane wax mixture and D-003. Octacosanoic acid can be formed in the liver from Octacosanol (HY-N6811) and inhibits nitric oxide (NO) production in LPS-activated macrophages and LPS-induced splenic lymphocyte proliferation. Octacosanoic acid can be used in anti-inflammatory and lipid metabolism-related research.

For research use only. We do not sell to patients.

Purity : 98.0%
CAS No.: 506-48-9
Formula: C₂₈H₅₆O₂
Molecular Weight:424.74

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Octacosanoic acid Chemical Structure

CAS No.: 506-48-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

IC₅₀ & Target

Human Endogenous Metabolite

All NO Synthase Isoforms :

In Vitro

Octacosanoic acid (Montanic acid) (1.83-3.32 mg/g extract/9-14 mg/kg dw; 8 h) is present in the root lipophilic extracts of green, orange, and red varieties of Opuntia ficus-indica, with the highest relative content in the extract of the red variety, at 3.32 mg/g^[6].
Octacosanoic acid (compound 1) (1-100 μg/mL; 14 h) reduces NO production in LPS-stimulated rat peritoneal macrophages, decreasing NO to 19.74 μg/mL at 100 μg/mL^[7].
Octacosanoic acid (1-100 μg/mL; 44 h) inhibits LPS-induced mouse splenic lymphocyte proliferation in a dose-dependent manner, with a PI of 0.966 at 100 μg/mL^[7].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 506-48-9
Appearance Solid
Molecular Weight 424.74
Formula C₂₈H₅₆O₂
Color White to light yellow
SMILES

CCCCCCCCCCCCCCCCCCCCCCCCCCCC(O)=O
Synonyms

Montanic acid
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : < 1 mg/mL (insoluble or slightly soluble)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mendoza MS, et al. Comparison of the effects of D-003 and policosanol on lipid profile and endothelial cells in normocholesterolemic rabbits. Current therapeutic research. 2001 Mar 1;62(3):209-20.

[2]. Hil AL, et al. Chemical composition and antimicrobial activity of the hexanic extract from the leaves and stems of Croton micradenus (Euphorbiaceae). Acta Botánica Cubana. 2023 Jul 10;222:cu-id.

[3]. Noa M, et al. D-003 does not possess oestrogenic potential in-vivo: findings of the uterotrophic assay. The Journal of pharmacy and pharmacology. 2007 Oct;59(10):1433-7.

[4]. Molina V, et al. Synergistic effect of D-003 and aspirin on experimental thrombosis models. Prostaglandins, leukotrienes, and essential fatty acids. 2003 May;68(5):305-10.

[5]. Ety Sari Handayani, et al. Black sugarcane decoction reduces rat brain ischemia. Univ Med. 2016;35(1):40-45.

[6]. Benramdane E, et al. Lipophilic Compounds and Antibacterial Activity of Opuntia ficus-indica Root Extracts from Algeria. Int J Mol Sci. 2022 Sep 22;23(19):11161.

[7]. Yang NianYun YN, et al. Immunological activities of components from leaves of Liriodendron chinensis. Chinese Herbal Medicines, Volume 7, Issue 3, 2015, Pages 279-282, ISSN 1674-6384,

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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