Parawixin10
Parawixin10 (Compound 2) is an N-acylpolyamine. Parawixin10 fails to enhance glutamate uptake in radioligand uptake assays of EAAT1, EAAT2 or EAAT3. Parawixin10 exhibits no positive allosteric modulatory activity in radioligand uptake assays of EAAT1−EAAT3, nor can it improve neuronal survival rates in mice in a dose-dependent and statistically significant manner. Parawixin10 has no neuroprotective activity.
For research use only. We do not sell to patients.
- Formula: C30H55I2N9O3
- Molecular Weight:843.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
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EAAT1 |
EAAT2 |
EAAT3 |
In Vitro
Chemical Information
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Molecular Weight 843.63
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Formula C30H55I2N9O3
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SMILES
C[N+](C)(CCCC[N+](C)(C)CCCNC(CC1=CNC2=CC=CC(O)=C21)=O)CCCNC([C@H](CCCNC(N)=N)N)=O.[I-].[I-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Doroudian Y, et al. The N-Acylpolyamine Structure Assigned as Parawixin10 Does Not Display Positive Allosteric Modulatory Activity in EAAT1-3 Radioligand Uptake Assays, nor Does It Enhance Neuronal Survival in Mice in a Dose-Dependent and Statistically Significant Way. ACS Chem Neurosci. 2026;17(8):1530-1539. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Parawixin10 Related Classifications
HY-182941 Related Classifications
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