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Cat. No.: HY-190275

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PDE3A/B-IN-3

PDE3A/B-IN-3 is a PDE3A and PDE3B inhibitor. PDE3A/B-IN-3 can be used for cervical cancer research.

For research use only. We do not sell to patients.

CAS No.: 2275774-55-3
Formula: C₁₄H₈F₆N₄O₂
Molecular Weight:378.23

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PDE3A/B-IN-3 Chemical Structure

CAS No.: 2275774-55-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

PDE3A/B-IN-3 is a PDE3A and PDE3B inhibitor. PDE3A/B-IN-3 can be used for cervical cancer research^[1].

IC₅₀ & Target

^[1]

PDE3A

200 nM (IC₅₀)

PDE3B

160 nM (IC₅₀)

All Phosphodiesterase (PDE) Isoforms :

In Vitro

PDE3A/B-IN-3 (Example 130) inhibits PDE3A and PDE3B in Sf9 cell extracts overexpressing PDE3A/B, with IC₅₀ values of 200 and 160 nM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2275774-55-3
Molecular Weight 378.23
Formula C₁₄H₈F₆N₄O₂
SMILES

O=C1NN=C(C2=CC(C(F)(F)F)=C(C3=C(C(F)(F)F)NN=C3)C=C2)CO1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Manuel ELLERMANN, et al. Dihydrooxadiazinones. WO2019025562A1. WIPO (PCT). 2018-08-01.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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PDE3A/B-IN-3

All Phosphodiesterase (PDE) Isoforms

Biological Activity

Description

IC50 & Target

In Vitro

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

PDE3A/B-IN-3 Related Classifications

HY-190275 Related Classifications

Bioz

Keywords

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