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Cat. No.: HY-N21637

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Phanginin L

Phanginin L is a cassane-type furanoditerpenoid compound found in the seeds of Caesalpinia sappan Linn. Phanginin L exhibits moderate cytotoxicity against HepG2 cancer cells, while it shows no activity against SF-268 and MCF-7 cancer cells. Phanginin L can be used in liver cancer-related research.

For research use only. We do not sell to patients.

CAS No.: 1426297-40-6
Formula: C₂₃H₃₀O₆
Molecular Weight:402.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Phanginin L Chemical Structure

CAS No.: 1426297-40-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC50	9.13 μg/mL	Cytotoxicity against human HepG2 hepatocellular carcinoma cells assessed by MTT assay. Cytotoxicity against human HepG2 hepatocellular carcinoma cells assessed by MTT assay.	SP.J.1009.2012.00218

In Vitro

Anti-cancer

Phanginin L (compound 1) exhibits moderate activity against the HepG2 cell line with an IC₅₀ of 9.13 μg/mL, but shows no activity against SF-268 and MCF-7 cells (IC₅₀ > 10 μg/mL)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 1426297-40-6
Molecular Weight 402.48
Formula C₂₃H₃₀O₆
SMILES

O=C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC4=C(C=CO4)[C@@H]3C)([H])[C@](C)([C@H](CC1)OC(C)=O)C(OC)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang J Y, et al. Two new cassane diterpenoids from the seeds of Caesalpinia sappan Linn. Chinese Journal of Natural Medicines, 2012, 10(3): 218-221.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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