Phenylglyoxylic acid-d5
Based on 1 Customer Validation
Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) is a deuterium labeled Phenylglyoxylic acid (HY-W010255). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.
For research use only. We do not sell to patients.
- Purity : 99.90%
- CAS No.: 1217089-53-6
- Formula: C8HD5O3
- Molecular Weight:155.16
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217089-53-6
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Unlabeled CAS 611-73-4
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Appearance Solid
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Molecular Weight 155.16
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Formula C8HD5O3
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Color Off-white to light yellow
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SMILES
OC(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O
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Synonyms
Benzoylformic acid-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (644.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110. [Content Brief]
[3]. Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4450 mL | 32.2248 mL | 64.4496 mL | 161.1240 mL |
| 5 mM | 1.2890 mL | 6.4450 mL | 12.8899 mL | 32.2248 mL | |
| 10 mM | 0.6445 mL | 3.2225 mL | 6.4450 mL | 16.1124 mL | |
| 15 mM | 0.4297 mL | 2.1483 mL | 4.2966 mL | 10.7416 mL | |
| 20 mM | 0.3222 mL | 1.6112 mL | 3.2225 mL | 8.0562 mL | |
| 25 mM | 0.2578 mL | 1.2890 mL | 2.5780 mL | 6.4450 mL | |
| 30 mM | 0.2148 mL | 1.0742 mL | 2.1483 mL | 5.3708 mL | |
| 40 mM | 0.1611 mL | 0.8056 mL | 1.6112 mL | 4.0281 mL | |
| 50 mM | 0.1289 mL | 0.6445 mL | 1.2890 mL | 3.2225 mL | |
| 60 mM | 0.1074 mL | 0.5371 mL | 1.0742 mL | 2.6854 mL | |
| 80 mM | 0.0806 mL | 0.4028 mL | 0.8056 mL | 2.0140 mL | |
| 100 mM | 0.0644 mL | 0.3222 mL | 0.6445 mL | 1.6112 mL |
Phenylglyoxylic acid-d5 Related Classifications
HY-W010255S Related Classifications
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