Piriprost
Piriprost (U-60257) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost increases the activity of alkaline phosphatase (ALP). Piriprost antagonizes contractions induced by leukotriene C/D in vitro. Piriprost is used in asthma research.
For research use only. We do not sell to patients.
- CAS No.: 79672-88-1
- Formula: C26H35NO4
- Molecular Weight:425.57
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 79672-88-1
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Molecular Weight 425.57
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Formula C26H35NO4
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SMILES
C(CCCC(O)=O)C=1N(C2=C(C1)[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C2)C3=CC=CC=C3
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Synonyms
U-60257
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. van der Meer JW, et al. Abstract!. The Netherlands journal of medicine. 2002 Dec;60(11):418. [Content Brief]
[2]. Cejic SS, et al. Examination of the effects of piriprost (U-60,257B) on alkaline phosphatase activity of rat endometrial stromal cells in vitro. Prostaglandins. 1991 Aug;42(2):179-89. [Content Brief]
[3]. McCormack DG, et al. The contrasting influence of two lipoxygenase inhibitors on hypoxic pulmonary vasoconstriction in anesthetized pigs. Am Rev Respir Dis. 1989 Jan;139(1):100-5. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Piriprost Related Classifications
HY-106064 Related Classifications
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