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Cat. No.: HY-186335

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PKM2 activator 12

For research use only. We do not sell to patients.

CAS No.: 3083982-21-9
Formula: C₂₃H₂₆FN₃O₃S₂
Molecular Weight:475.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PKM2 activator 12 Chemical Structure

CAS No.: 3083982-21-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

In Vitro

PKM2 is the M2 isoform of pyruvate kinase, a key rate-limiting enzyme in glycolysis. It can switch between a tetramer (high enzymatic activity) and a dimer (low enzymatic activity, nuclear localization), regulates the Warburg effect, and participates in tumor metabolism, proliferation, and transcriptional regulation, making it a popular target in cancer research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3083982-21-9
Molecular Weight 475.60
Formula C₂₃H₂₆FN₃O₃S₂
SMILES

O=C(N1CCC(CC1)(CC(C)C)F)C2=CC=C(NS(=O)(C3=C4N=CSC4=CC=C3)=O)C=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

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