Pomalidomide-PEG3-acid
Based on 1 Customer Validation
Pomalidomide-PEG3-acid is a synthetic E3 ubiquitin ligase ligand-linker conjugate that can be used to synthesize PROTACs such as AY-4 (HY-174867).
For research use only. We do not sell to patients.
- Purity : 99.57%
- CAS No.: 2143097-07-6
- Formula: C21H25N3O9
- Molecular Weight:463.44
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2143097-07-6
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Appearance Solid
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Molecular Weight 463.44
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Formula C21H25N3O9
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Color Light yellow to yellow
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SMILES
O=C(O)COCCOCCOCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (107.89 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1578 mL | 10.7889 mL | 21.5778 mL | 53.9444 mL |
| 5 mM | 0.4316 mL | 2.1578 mL | 4.3156 mL | 10.7889 mL | |
| 10 mM | 0.2158 mL | 1.0789 mL | 2.1578 mL | 5.3944 mL | |
| 15 mM | 0.1439 mL | 0.7193 mL | 1.4385 mL | 3.5963 mL | |
| 20 mM | 0.1079 mL | 0.5394 mL | 1.0789 mL | 2.6972 mL | |
| 25 mM | 0.0863 mL | 0.4316 mL | 0.8631 mL | 2.1578 mL | |
| 30 mM | 0.0719 mL | 0.3596 mL | 0.7193 mL | 1.7981 mL | |
| 40 mM | 0.0539 mL | 0.2697 mL | 0.5394 mL | 1.3486 mL | |
| 50 mM | 0.0432 mL | 0.2158 mL | 0.4316 mL | 1.0789 mL | |
| 60 mM | 0.0360 mL | 0.1798 mL | 0.3596 mL | 0.8991 mL | |
| 80 mM | 0.0270 mL | 0.1349 mL | 0.2697 mL | 0.6743 mL | |
| 100 mM | 0.0216 mL | 0.1079 mL | 0.2158 mL | 0.5394 mL |