Pomalidomide-PEG6-C2-COOH
Based on 1 Customer Validation
Pomalidomide-PEG6-C2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide (HY-10984) based cereblon ligand and 6-unit PEG linker used in PROTAC technology.
For research use only. We do not sell to patients.
- Purity : 98.46%
- CAS No.: 2225148-49-0
- Formula: C28H39N3O12
- Molecular Weight:609.62
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-133699
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Pomalidomide-PEG2-COOHE3 Ligase Ligand-Linker Conjugate -
HY-131647
Pomalidomide 4'-PEG5-acidE3 Ligase Ligand-Linker Conjugates -
HY-133138
Pomalidomide-PEG1-azideE3 Ligase Lgand-Linker Conjugate -
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Thalidomide-NH-PEG3-propionic acidE3 Ligase Ligand-Linker Conjugate -
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Pomalidomide-PEG1-C2-COOHE3 Ligase Ligand-Linker Conjugate
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
Description
Chemical Information
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CAS No. 2225148-49-0
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Appearance Viscous Liquid
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Molecular Weight 609.62
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Formula C28H39N3O12
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Color Light yellow to yellow
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCNC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)O
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Synonyms
Pomalidomide-PEG6-COOH
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 33.33 mg/mL (54.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6404 mL | 8.2018 mL | 16.4037 mL | 41.0092 mL |
| 5 mM | 0.3281 mL | 1.6404 mL | 3.2807 mL | 8.2018 mL | |
| 10 mM | 0.1640 mL | 0.8202 mL | 1.6404 mL | 4.1009 mL | |
| 15 mM | 0.1094 mL | 0.5468 mL | 1.0936 mL | 2.7339 mL | |
| 20 mM | 0.0820 mL | 0.4101 mL | 0.8202 mL | 2.0505 mL | |
| 25 mM | 0.0656 mL | 0.3281 mL | 0.6561 mL | 1.6404 mL | |
| 30 mM | 0.0547 mL | 0.2734 mL | 0.5468 mL | 1.3670 mL | |
| 40 mM | 0.0410 mL | 0.2050 mL | 0.4101 mL | 1.0252 mL | |
| 50 mM | 0.0328 mL | 0.1640 mL | 0.3281 mL | 0.8202 mL |
Pomalidomide-PEG6-C2-COOH Related Classifications
HY-141658 Related Classifications
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