Cyclin-Dependent Kinase 3 (CDK3)
CDK3 is among the least characterized members of the cyclin-dependent kinase family. It partners with cyclin C and has been reported to phosphorylate the retinoblastoma protein, driving quiescent cells from G0 into G1 and supporting cell-cycle re-entry; roles in keratinocyte proliferation and in RNA-related regulation through cyclin C have also been described. Expression is detected in a variety of tissues, and unlike the classical cell-cycle CDKs, CDK3 lacks extensive inhibitor validation. Recombinant CDK3 protein provides a defined reagent for kinase profiling, substrate identification and selectivity testing of pan-CDK inhibitors against this understudied paralog.
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Cyclin-Dependent Kinase 3 (CDK3) Recombinant Proteins (6)
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Inhibitors & Agonists (28)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
