Cathelicidins: microbicidal activity, mechanisms of action, and roles in innate immunity
- Microbes Infect. 2002 Mar;4(3):361-72. doi: 10.1016/s1286-4579(02)01549-6.
Affiliations
- 1. Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5802, USA.
PMID: 11909747
DOI: 10.1016/s1286-4579(02)01549-6
Abstract
Antimicrobial Peptides are important host-defense molecules of innate immunity. Cathelicidins are a diverse family of potent, rapidly acting and broadly effective Antimicrobial Peptides, which are produced by a variety of cells. This review examines the classification, antimicrobial spectrum, mechanism of action, and regulation of cathelicidins.