In vitro antibacterial activity of DX-619, a novel des-fluoro(6) quinolone

  • Antimicrob Agents Chemother. 2005 Jul;49(7):3040-5. doi: 10.1128/AAC.49.7.3040-3045.2005.
Katsuko Fujikawa  1 ,  Megumi Chiba ,  Mayumi Tanaka ,  Kenichi Sato
Affiliations
  • 1. New Product Research Laboratories I, Daiichi Pharmaceutical Co. Ltd., 16-13 Kitakasai 1-Chome, Edogawa-ku, Tokyo 134-8630, Japan. [email protected]
PMID: 15980395 DOI: 10.1128/AAC.49.7.3040-3045.2005
Abstract

The in vitro activities of DX-619, des-fluoro(6) Quinolone, against 1,208 clinical isolates were examined. DX-619 was particularly potent against staphylococci, including ciprofloxacin- and methicillin-resistant strains; the MIC at which 90% of the strains tested were inhibited was 0.5 microg/ml. In addition, DX-619 was also active against gram-negative bacteria.

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