Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus

  • Org Lett. 2006 Aug 31;8(18):4067-70. doi: 10.1021/ol061556f.
Katherine N Maloney  1 ,  Wenshan Hao ,  Jun Xu ,  Jay Gibbons ,  John Hucul ,  Deborah Roll ,  Sean F Brady ,  Frank C Schroeder ,  Jon Clardy
Affiliations
  • 1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Abstract

Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus, inhibits signaling by the transcription factor STAT3.

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