Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging

  • Chem Commun (Camb). 2010 Jun 21;46(23):4139-41. doi: 10.1039/c0cc00179a.
Youngmin You  1 ,  Elisa Tomat ,  Kevin Hwang ,  Tatjana Atanasijevic ,  Wonwoo Nam ,  Alan P Jasanoff ,  Stephen J Lippard
Affiliations
  • 1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
PMID: 20454746 DOI: 10.1039/c0cc00179a
Abstract

A paramagnetic manganese complex of a fluorescein-based probe affords a dual-modality zinc sensor featuring an improved fluorescence dynamic range and an MRI readout.

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