Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization

  • Haematologica. 2017 May;102(5):e170-e174. doi: 10.3324/haematol.2016.161570.
Julia Schanda  1 ,  Chun-Wei Lee  2 ,  Katharina Wohlan  2 ,  Uta Müller-Kuller  1  3 ,  Hana Kunkel  1 ,  Isabell Quagliano-Lo Coco  1  3 ,  Stefan Stein  1 ,  Alexander Metz  4 ,  Joachim Koch  1 ,  Jörn Lausen  1 ,  Uwe Platzbecker  5 ,  Hind Medyouf  1 ,  Holger Gohlke  4 ,  Michael Heuser  2 ,  Matthias Eder  2 ,  Manuel Grez  6 ,  Michaela Scherr  2 ,  Christian Wichmann  1  7
Affiliations
  • 1. Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
  • 2. Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Germany.
  • 3. German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • 4. Institute for Pharmaceutical and Medicinal Chemistry, Department of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany.
  • 5. Department of Hematology, Medical Clinic and Polyclinic I, University Hospital Carl Gustav Carus, Dresden, Germany.
  • 6. Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany [email protected].
  • 7. Department of Transfusion Medicine, Cell Therapeutics and Hemostaseology, Ludwig-Maximilian University Hospital, Munich, Germany.
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