(rac)-AG-205
(rac)-AG-205 is an isomer of AG-205 (HY-115625). AG-205 is an antagonist of progesterone receptor membrane component 1 (PGRMC1) and an inhibitor of ceramide galactosyltransferase (CGT); it can be used in research related to renal cancer and breast cancer..
For research use only. We do not sell to patients.
- CAS No.: 442656-02-2
- Formula: C22H23ClN6OS
- Molecular Weight:454.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-16508
Ulipristal acetateSelective Progesterone Receptor Modulator -
HY-B0257A
DydrogesteroneProgestogen -
HY-14959
UlipristalSelective Progesterone Receptor Modulator -
HY-13071
NestoronProgesterone Receptor Agonist -
HY-15606
TanaprogetProgesterone Receptor Agonist -
HY-119433
Asoprisnil -
HY-B1089
Ethynodiol diacetateProgesterone Receptor Agonist -
HY-11028
PF-02413873Progesterone Receptor Antagonist -
HY-16508R
Ulipristal acetate (Standard)Selective Progesterone Receptor Modulator -
HY-B0257AR
Dydrogesterone (Standard)Progestogen -
HY-B1089R
Ethynodiol diacetate (Standard)Progesterone Receptor Agonist
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 442656-02-2
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Molecular Weight 454.98
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Formula C22H23ClN6OS
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SMILES
CC1=CC2=C(C=C1)N(C3C2CN(CC3)C)C(CSC4=NN=NN4C5=CC=C(C=C5)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang-Eckhardt L, et al. The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide. Cells. 2021;10(12):3520. Published 2021 Dec 13. [Content Brief]
[3]. Thieffry C, et al. AG-205 Upregulates Enzymes Involved in Cholesterol Biosynthesis and Steroidogenesis in Human Endometrial Cells Independently of PGRMC1 and Related MAPR Proteins. Biomolecules. 2021;11(10):1472. Published 2021 Oct 6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(rac)-AG-205 Related Classifications
HY-121012 Related Classifications
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