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Cat. No.: HY-N0684B

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(Rac)-Vitamin K1

Name: (Rac)-Vitamin K1
Brand: MedChemExpress
SKU: HY-N0684B
Availability: PreOrder

(Synonyms: (Rac)-Phylloquinone; (Rac)-Phytomenadione)

(Rac)-Vitamin K1 ((Rac)-Phylloquinone; (Rac)-Phytomenadione) is a vitamin (phylloquinone) found in Urtica dioica that targets angiotensin-converting enzyme 2 (ACE-2). (Rac)-Vitamin K1 can be used in studies related to coronavirus disease 2019 (COVID-19).

For research use only. We do not sell to patients.

CAS No.: 2581046-19-5
Formula: C₃₁H₄₆O₂
Molecular Weight:450.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(Rac)-Vitamin K1 Chemical Structure

CAS No.: 2581046-19-5

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Biological Activity
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Chemical Information
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Biological Activity

Description

In Vitro

Cardiovascular Regulation

(Rac)-Vitamin K1 (Table 1, SI. no.37) binds to human ACE-2 receptor (PDB ID: 1R4L) with a binding energy of -7.9 kcal/mol via a hydrogen bond with Gln 98^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2581046-19-5
Molecular Weight 450.70
Formula C₃₁H₄₆O₂
SMILES

O=C1C2=CC=CC=C2C(C(C)=C1C/C=C(C)/CCCC(C)CCCC(C)CCCC(C)C)=O
Synonyms

(Rac)-Phylloquinone; (Rac)-Phytomenadione
Structure Classification
- Quinones
- Naphthalene Quinones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Upreti S, et al. Identification of novel inhibitors of angiotensin-converting enzyme 2 (ACE-2) receptor from Urtica dioica to combat coronavirus disease 2019 (COVID-19). Molecular diversity. 2021 Aug;25(3):1795-1809. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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