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Cat. No.: HY-133158B

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S-Adenosylmethioninamine phosphate

S-Adenosylmethioninamine phosphate is a decarboxylated sulfonucleoside metabolite of S-adenosylmethionine. S-Adenosylmethioninamine phosphate serves as an aminopropyl donor in polyamine synthesis, promoting the generation of spermine and spermidine from Putrescine (1,4-Butanediamine) (HY-N2407). S-Adenosylmethioninamine phosphate can be used in neurotoxicity research.

For research use only. We do not sell to patients.

Formula: C₁₄H₂₅N₆O₇PS
Molecular Weight:452.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

S-Adenosylmethioninamine phosphate Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

In Vitro

S-Adenosylmethioninamine (dcSAM) phosphate is identified and quantified in the cell-free supernatant of Pseudomonas aeruginosa (BAA-47) at a concentration of 32.2 nM, its Ss and Rs diastereomers are successfully chromatographically separated, and its MS/MS fragmentation is characterized^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Neurotoxicity Study

Chemical Information

Molecular Weight 452.42
Formula C₁₄H₂₅N₆O₇PS
SMILES

OP(O)([O-])=O.NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](C[S+](C)CCCN)O3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Murín R, et al. Role of S-adenosylmethionine cycle in carcinogenesis. General physiology and biophysics. 2017 Dec;36(5):513-520.

[2]. Cataldi TR, et al. Analysis of S-adenosylmethionine and related sulfur metabolites in bacterial isolates of Pseudomonas aeruginosa (BAA-47) by liquid chromatography/electrospray ionization coupled to a hybrid linear quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry. Rapid communications in mass spectrometry : RCM. 2009 Nov;23(21):3465-77.

[3]. Jiang J, et al. Potential neurotoxicity of prenatal exposure to sevoflurane on offspring: Metabolomics investigation on neurodevelopment and underlying mechanism. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2017 Nov;62:46-53.

[4]. Liu J, et al. Unveiling the therapeutic mechanisms of Saorilao-4 decoction in pulmonary fibrosis through metabolomics and transcriptomics. Frontiers in nutrition. 2025;12:1612149.

[5]. Maclean KN, et al. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis. Molecular genetics and metabolism. 2021 Feb;132(2):128-138.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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