SAMHD1 ligand-1
SAMHD1 ligand-1 is a SAMHD1 ligand that can be used for the synthesis of PROTAC SAMHD1 Degrader-1 (HY-182970).
For research use only. We do not sell to patients.
- Formula: C27H32ClN7O3
- Molecular Weight:538.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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SAMHD1 |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 538.04
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Formula C27H32ClN7O3
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SMILES
OCCCCN(N=C1)C(N=C2NC(CC3)CCN3CC(C=C4)=CC(Cl)=C4OC5=CC(N)=CC=C5)=C1C(N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)