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Cat. No.: HY-P1138A

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Scrambled 10Panx TFA

Name: Scrambled 10Panx TFA
Brand: MedChemExpress
SKU: HY-P1138A
Price: 105.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: FSVYWAQADR TFA)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Scrambled 10Panx TFA (FSVYWAQADR TFA) is an inactive scrambled control peptide of the Pannexin-1 hemichannel inhibitory peptide 10panx.

For research use only. We do not sell to patients.

Formula: C₅₈H₇₉N₁₅O₁₆·xC₂HF₃O₂
Molecular Weight:1242.34 (free base)

Storage:

Sealed storage, away from moisture.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Scrambled 10Panx TFA Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

Scrambled 10Panx TFA (FSVYWAQADR TFA) is an inactive scrambled control peptide of the Pannexin-1 hemichannel inhibitory peptide 10panx^[1]^[2].

In Vitro

Scrambled 10Panx TFA serves as a control peptide, which can be used to determine whether other experimental conditions or peptides exert effects through specific molecular mechanisms^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Scrambled 10Panx (TFA) (100 μM, 6 μl; intrasciatic injection; single dose) has no effect on CCI-induced mechanical or thermal hyperalgesia in adult male CD1 mice^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

CD1 (adult male, 6-8 weeks, chronic constriction injury model)^[2]
Dosage:

100 μM, 6 μl
Administration:

intrasciatic injection; single dose
Result:

Did not alter CCI-induced mechanical or thermal hyperalgesia.
Left mechanical and thermal pain thresholds at reduced levels seen in vehicle-treated CCI mice.
Showed no significant improvement across days 1, 2, 3, 4, and 6 post-injection.

Chemical Information

Appearance Solid
Molecular Weight 1242.34 (free base)
Formula C₅₈H₇₉N₁₅O₁₆·xC₂HF₃O₂
SMILES

O=C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CC=CC=C4)N.OC(C(F)(F)F)=O.[x]
Synonyms

FSVYWAQADR TFA
Sequence

Phe-Ser-Val-Tyr-Trp-Ala-Gln-Ala-Asp-Arg
Sequence Shortening

FSVYWAQADR
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Journal Impact Factor

Autophagy

Metabolites released from apoptotic cells in central nervous system orchestrates the pathological process of Alzheimer disease through improving autophagy. [Abstract]

2026 Jan 19:1-16. PMID: 41518198

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Thompson RJ, et al. Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus. Science (New York, N.Y.). 2008 Dec 05;322(5907):1555-9. [Content Brief]

[2]. Wang Q, et al. Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses. Journal of neuroinflammation. 2022 Oct 04;19(1):244.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

Scrambled 10Panx TFA

1 Cited Publications

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (1)
Solvent & Solubility
- In Vitro
Purity & Documentation
References

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Scrambled 10Panx TFA

Publications Citing Use of MedChemExpress (MCE) Scrambled 10Panx TFA