SDH-IN-54
SDH-IN-54 is a succinate dehydrogenase (SDH) inhibitor (IC50 = 6.52 μg/mL against Sclerotinia sclerotiorum). SDH-IN-54 disrupts mycelial morphology and ultrastructure and inhibits sclerotium formation and germination by inhibiting mitochondrial respiratory chain enzymes. SDH-IN-54 exhibits protective and curative antifungal (fungal) efficacy against Sclerotinia sclerotiorum in rapeseed plants and can be used for research on rapeseed sclerotinia stem rot.
For research use only. We do not sell to patients.
- CAS No.: 3120515-12-7
- Formula: C17H11ClN2O3S
- Molecular Weight:358.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
SDH 6.52 μg/mL (IC50, Sclerotinia sclerotiorum) |
In Vitro
SDH-IN-54 (0.78-3.125 μg/mL) inhibits Sclerotinia sclerotiorum sclerotial formation (91.5% at 1.56 μg/mL) and germination (63.3% at 1.56 μg/mL; 43.3% at 0.78 μg/mL)[1].
SDH-IN-54 (50-200 μg/mL) produces in planta protective and curative effects against Sclerotinia sclerotiorum, with a protective effect of 90.8% and a curative effect of 80.3% at 200 μg/mL[1].
SDH-IN-54 (50 μg/mL; 0.3-25 μg/mL) inhibits the mycelial growth of S. sclerotiorum, with an EC50 of 0.61 μg/mL[1].
SDH-IN-54 (50-200 μg/mL) is evaluated on rapeseed leaves for its protective and curative activity against S. sclerotiorum[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3120515-12-7
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Molecular Weight 358.80
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Formula C17H11ClN2O3S
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SMILES
ClC1=CC=CC=C1C(NC2=CC=CC=C2C3=NC(C(O)=O)=CS3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDH-IN-54 Related Classifications
HY-189868 Related Classifications
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