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28 Results for "

π-stacking interactions

" in MedChemExpress (MCE) Product Catalog:

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IDO1/TDO-IN-4

1 Cited Publications

Cat. No.: HY-151108

CAS No.: 461424-21-5

Purity: 99.74%

Target:

Indoleamine 2,3-Dioxygenase (IDO)

Research Areas:

Neurological Disease Inflammation/Immunology

IDO1/TDO-IN-4 is a potent IDO1/TDO dual inhibitor, with IC₅₀ values of 3.53 μM (IDO1) and 1.15 μM (TDO). IDO1/TDO-IN-4 forms hydrogen bond with IDO1, and π−π stacking interaction with TDO. IDO1/TDO-IN-4 can be used in the research of depression, and depression-induced infectious, metabolic, and autoimmune disorders .

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Azaphen dihydrochloride monohydrate

1 Cited Publications

Cat. No.: HY-A0022A

CAS No.: 63302-99-8

Synonyms: Azafen monohydrate; Pipofezin dihydrochloride monohydrate; Pipofezine dihydrochloride monohydrate

Target:

Serotonin Transporter 5-HT Receptor

Research Areas:

Neurological Disease

Azaphen dihydrochloride monohydrate is an orally active tricyclic antidepressant that inhibits the reuptake of serotonin and monoamines, regulates the 5-HT2c receptor, and exerts sedative, antidepressant and anxiolytic effects. Azaphen dihydrochloride monohydrate increases the bioavailability of serotonin in the synaptic cleft, does not block muscarinic receptors or affect monoamine oxidase activity, and binds to the human serotonin transporter via salt bridges, π-stacking, π-cation and hydrophobic interactions. Azaphen dihydrochloride monohydrate can be used in studies related to depression .

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DL-Dopa

Cat. No.: HY-113404

CAS No.: 63-84-3

Purity: 98.58%

Category:

Ketones, Aldehydes, Acids Other Diseases Phenols Polyphenols Endogenous metabolite Disease Research Fields

Target:

Tyrosinase Dopamine Receptor

DL-Dopa is a dopamine precursor. It serves as a substrate for Mushroom Tyrosinase, which oxidizes it to dopaquinone, an intermediate in the DOPA-melanin polymerization process, and this reaction can be detected at 475 nm. DL-Dopa also forms synergistic hydrophobic and π-π stacking interactions with cationic surfactants. Its binding to cetylpyridinium chloride (HY-B1464) is stronger and exhibits better thermodynamic stability than its binding to benzalkonium chloride (HY-B2232). DL-Dopa can compensate for dopamine depletion in the brain and is applicable to research related to Parkinson's disease .

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Cellohexaose

Cat. No.: HY-N1915

CAS No.: 2478-35-5

Category:

Polysaccharides Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides

Target:

Biochemical Assay Reagents

Cellohexaose is a YKL-40 carbohydrate-binding ligand that occupies the primary carbohydrate-binding cleft through carbohydrate-π stacking and hydrogen-bonding interactions, and can serve as a bioinert spacer for hybrid glyco-nanolayers, modulating the surface density of bioactive shell hexaose to enhance TLR2-mediated responses. Cellohexaose is used in research on chronic inflammatory diseases and cancer .

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