Cyclohexanecarboxyl-CoA | MedChemExpress (MCE) Life Science Reagents

Research Areas:

Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

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17

Alisporivir

17 Cited Publications

Cat. No.: HY-12559

CAS No.: 254435-95-5

Purity: 98.08%

Synonyms: Debio-025; DEB-025

Target:

Cyclophilin HCV

Research Areas:

HCV Bacterial Antibiotic Reactive Oxygen Species (ROS)

Alisporivir (Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.

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8

Cyclo(Phe-Pro)

8 Cited Publications

Cat. No.: HY-P1934

CAS No.: 14705-60-3

Synonyms: Cyclo(phenylalanylprolyl); A-64863

Target:

Research Areas:

Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .

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4

Cyclo(RGDyK)

4 Cited Publications

Cat. No.: HY-100563A

CAS No.: 217099-14-4

Purity: 99.83%

Target:

Research Areas:

Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

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4

Cyclo(RGDyK) trifluoroacetate

4 Cited Publications

Cat. No.: HY-100563

CAS No.: 250612-42-1

Purity: 99.92%

Target:

Research Areas:

Cyclo(RGDyK) trifluoroacetate is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

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4

BQ-123

4 Cited Publications

Cat. No.: HY-12378

CAS No.: 136553-81-6

Purity: 99.82%

Target:

Endothelin Receptor

Research Areas:

Cardiovascular Disease

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC₅₀ of 7.3 nM and a K_i of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension .

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4

Murepavadin TFA

4 Cited Publications

Cat. No.: HY-P1674A

CAS No.: 3053070-05-3

Synonyms: POL7080 TFA

Target:

Bacterial Antibiotic

Research Areas:

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC₅₀ and MIC₉₀ values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .

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3

Astressin

3 Cited Publications

Cat. No.: HY-P0257

CAS No.: 170809-51-5

Target:

CRFR

Research Areas:

Neurological Disease

Astressin is a potent corticotropin releasing factor (CRF) antagonist.

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2

Cyclo(Arg-Gly-Asp-D-Phe-Cys)

2 Cited Publications

Cat. No.: HY-P2300

CAS No.: 862772-11-0

Synonyms: Cyclo(RGDfC)

Target:

Research Areas:

Antibiotic Bacterial Na+/K+ ATPase

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .

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2

Gramicidin S

2 Cited Publications

Cat. No.: HY-P5712

CAS No.: 113-73-5

Synonyms: Gramicidin soviet

Target:

Research Areas: