5 Results for "
FD 1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "FD 1" in MCE Product Catalog:
Cat. No.: HY-101748
CAS No.: 62987-05-7
Synonyms: 40497S; FD 1
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Tegadifur is a fluorine-containing and anti-metabolic agent.
Cat. No.: HY-187396
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FD1-C10-CB is a PROTAC degrader targeting the BRD4 protein. FD1-C10-CB binds to FEM1B to form a ternary complex with BRD4, achieving FEM1B-dependent degradation of BRD4 via the ubiquitin-proteasome system. FD1-C10-CB binds to CD36 to mediate endocytic cellular delivery, thereby enhancing its degrading activity. FD1-C10-CB mediates protein degradation through the Cullin-dependent ubiquitin-proteasome pathway, rather than the lysosomal autophagy pathway. FD1-C10-CB induces a decrease in BRD4 protein levels, and its degrading activity is competitively inhibited by FL47 or JQ1. FD1-C10-CB can be used in the research of breast cancer and osteosarcoma .
Cat. No.: HY-N3329
CAS No.: 113557-95-2