49 Results for "

PDX

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "PDX" in MCE Product Catalog:

41
Belinostat
Belinostat
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41 Publications Verification
Cat. No.: HY-10225
CAS No.: 866323-14-0
Purity:  99.95%
Synonyms: PXD101; PX105684; PDX 101
Target:  

HDAC Autophagy

Research Areas:  

Cancer

Belinostat (PXD101; PX105684) is a potent HDAC inhibitor with an IC50 of 27 nM in HeLa cell extracts.
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12
QC6352
QC6352
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12 Cited Publications
Cat. No.: HY-104048
CAS No.: 1851373-36-8
Purity:  99.13%
Target:  

Histone Demethylase

Research Areas:  

Cancer

QC6352 is an orally active KDM4 inhibitor with anti-tumor and anti-proliferative activity. QC6352 has in vivo inhibitory effects on PDX models of breast and colon cancer and reduces the number of chemoresistant cell populations. QC6352 inhibits KDM4 different isoforms with IC50s of 104 nM (KDM4A), 56 nM (KDM4B), 35 nM (KDM4C), and 104 nM (KDM4D), respectively. QC6352 has moderate inhibitory activity against KDM5 with an IC50 of 750 nM (KDM5B) .
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5
Isorhamnetin-3-O-glucoside
Isorhamnetin-3-O-glucoside
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5 Cited Publications
Cat. No.: HY-N0777
CAS No.: 5041-82-7
Category:  

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