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4 Results for "

12-OPDA

" in MedChemExpress (MCE) Product Catalog:

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12-Oxo phytodienoic acid (≥90%)

1 Cited Publications

Cat. No.: HY-118828B

CAS No.: 85551-10-6

Purity: 92.2%

Synonyms: 12-OPDA (≥90%)

Target:

NF-κB p38 MAPK TNF Receptor Interleukin Related NO Synthase Keap1-Nrf2

Research Areas:

Neurological Disease Inflammation/Immunology

12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%)) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) induces the expression of SOCS-1 and inhibits LPS (HY-D1056)-induced activation of the NF-κB and p38 MAPK signaling pathways. 12-Oxo phytodienoic acid (≥90%) inhibits LPS-induced expression of IL-6 and TNF-α, and reduces LPS-induced NO production by decreasing iNOS levels. 12-Oxo phytodienoic acid (≥90%) induces activation of the Nrf2 signaling cascade. 12-Oxo phytodienoic acid (≥90%) can be used for the research of neurodegenerative diseases .

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August 31

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12-Oxo phytodienoic acid

Cat. No.: HY-118828

CAS No.: 85551-10-6

Purity: ≥99.0%

Synonyms: 12-OPDA

Target:

Keap1-Nrf2 p38 MAPK Interleukin Related TNF Receptor NF-κB NO Synthase

Research Areas:

Neurological Disease Inflammation/Immunology

12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056)-activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research .

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