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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
2,3-DPG
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "2,3-DPG" in MCE Product Catalog:
Target:
Synonyms: 2,3-DPG pentasodium salt
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2,3-Diphospho-D-glyceric acid (2,3-DPG) pentasodium salt is a hemoglobin binder and vascular calcification inhibitor that reduces the oxygen affinity of hemoglobin. 2,3-Diphospho-D-glyceric acid pentasodium salt also specifically delays the transformation of colloidal calciprotein particles into crystalline forms, thereby effectively inhibiting vascular smooth muscle cell calcification without affecting the normal formation of osteoid nodules in osteoblast-like cells. 2,3-Diphospho-D-glyceric acid pentasodium salt shows no cytotoxicity to tested cell lines and only weakly interferes with β-hematin formation mediated by glyceryl monopalmitate. 2,3-Diphospho-D-glyceric acid pentasodium salt can be used to study the pathological mechanisms of vascular calcification and malaria-related conditions .
Synonyms: 2,3-DPG pentasodium
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2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate metabolite of the 2,3-BPG shunt in erythrocytes, capable of binding to hemoglobin and modulating oxygen affinity. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxyhemoglobin T-state conformation, reduces hemoglobin oxygen affinity, and promotes oxygen release in tissues. 2,3-Diphosphoglyceric acid pentasodium inhibits the growth of Plasmodium falciparum within erythrocytes without causing hemolysis or a decrease in ATP levels. 2,3-Diphosphoglyceric acid pentasodium is useful for research related to malaria and Alzheimer's disease .
Cat. No.: HY-113050B
CAS No.: 62868-79-5
Synonyms: 2,3-DPG (pentacyclohexylamine)
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2,3-Diphosphoglyceric acid (2,3-DPG) pentacyclohexylamine is an intermediate metabolite of the 2,3-BPG shunt in erythrocytes, capable of binding to hemoglobin and modulating oxygen affinity. 2,3-Diphosphoglyceric acid pentacyclohexylamine stabilizes the deoxyhemoglobin T-state conformation, reduces hemoglobin oxygen affinity, and promotes oxygen release in tissues. 2,3-Diphosphoglyceric acid pentacyclohexylamine inhibits the growth of Plasmodium falciparum within erythrocytes without causing hemolysis or a decrease in ATP levels. 2,3-Diphosphoglyceric acid pentacyclohexylamine is useful for research related to malaria and Alzheimer's disease .
Cat. No.: HY-12689C
CAS No.: 2559738-69-9
Synonyms: AG-348 hydrochloride
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Mitapivat (AG-348) hydrochloride is an orally active and selective allosteric pyruvate kinase R (PK-R) activator. Mitapivat hydrochloride accelerates the reaction of PK-R catalyzing the conversion of phosphoenolpyruvate to pyruvate, thereby promoting the glycolytic pathway, increasing the production of adenosine triphosphate (ATP) in red blood cells, and reducing the level of 2,3-diphosphoglycerate (2,3-DPG). Mitapivat hydrochloride is promising for research of pyruvate kinase deficiency and other anemia-related diseases .
Cat. No.: HY-W751808S
CAS No.: 2726226-14-6
Synonyms: 2,3-DPG-13C3
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Protocols
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