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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
2-dioxygenase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "2-dioxygenase" in MCE Product Catalog:
Target:
Research Areas:
4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase [2].
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3,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71 .
Cat. No.: HY-E71519
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2-Deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) requires ferrous iron. 2-Deoxymugineic-acid 2'-dioxygenase (EC 1.14.11.24) catalyzes the hydroxylation of 3-epimylated-2'-deoxymugineic acid to 3-epimylated mugine.
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3,6-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71 .
Cat. No.: HY-W016584
CAS No.: 3428-24-8
4,5-Dichlorocatechol is a substrate of the broad-spectrum chlorocatechol 1,2-dioxygenase of pseudomonas chlororaphis RW71. The Ki values for 4,5-dichlorocatechol is 30 nM for the dioxygenase of the Chlorobenzoate-degrading strain Pseudomonas putida AC27 and 4 nM for the dioxygenase of Acidovorax sp. strain PS14 .
Cat. No.: HY-E71536
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2-Halobenzoate 1,2-dioxygenase (EC 1.14.12.13) is a multicomponent enzyme system composed of a dioxygenase component and an electron transfer component.
Cat. No.: HY-E71388
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1-Hydroxy-2-naphthoate 1,2-dioxygenase (EC 1.13.11.38) requires Fe2+.
Cat. No.: HY-E71066
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(3R,6E)-Nerolidol synthase (EC 1.13.11.80) , characterized from bacteria Streptomyces toyocaensis and Amycolatopsis orientalis, is involved in the biosynthesis of (3,5-dihydroxyphenyl) glycine, a component of the glycopeptide antibiotic vancomycin.
Cat. No.: HY-133597R
CAS No.: 2138-22-9
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4-Chlorocatechol (Standard) is the analytical standard of 4-Chlorocatechol. This product is intended for research and analytical applications. 4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase [2].
Cat. No.: HY-E71444
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2,6-Dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) cleaves the products from biphenol, 3-isopropylcatechol and 3-methylcatechol produced by EC 1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase, by ring-fission at a -CO-C bond.
Cat. No.: HY-108046
CAS No.: 869743-37-3
Synonyms: UP302
Target:
Tyrosinase PI3K Akt Bcl-2 Family Caspase PINK1/Parkin Atg8/LC3 Mitophagy Apoptosis Reactive Oxygen Species (ROS)
Research Areas:
Nivitol (UP302) is a natural phenolic compound discovered from Dianella ensifolia and also acts as a Tyrosinase inhibitor. Nivitol competitively and reversibly inhibits tyrosinase, suppressing melanin production. Nivitol inhibits homogentisate 1,2-dioxygenase (HGD). In human leukemia cells, Nivitol inhibits PI3K/AKT pathway phosphorylation, increases ROS, decreases mitochondrial membrane potential, and induces G2/M cell cycle arrest, apoptosis, and PINK1/Parkin-mediated mitophagy. Nivitol exhibits inhibition of tumor growth in the MV411 xenograft mouse model. Nivitol is used for research on exogenous ochronosis, hyperpigmentation, and leukemia [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
