136 Results for "

20S

" in MedChemExpress (MCE) Product Catalog:
Products (136)

136 Results for "20S" in MCE Product Catalog:

286
Bortezomib
Bortezomib
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286 Publications Verification
Cat. No.: HY-10227
CAS No.: 179324-69-7
Purity:  99.91%
Synonyms: PS-341; LDP-341; NSC 681239
Target:  

Proteasome NF-κB Apoptosis Autophagy TREM receptor Ligands for Target Protein for PROTAC

Research Areas:  

Cancer

Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM) . Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs) .
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69
Celastrol
Celastrol
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69 Cited Publications
Cat. No.: HY-13067
CAS No.: 34157-83-0
Purity:  99.64%
Synonyms: Tripterine; Tripterin
Category:  

Triterpenes Anti-aging Celastraceae Extract Terpenoids Plants 500 - Internal Server Error | MedChemExpress

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