346 Results for "

2C protein

" in MedChemExpress (MCE) Product Catalog:
Products (346)

346 Results for "2C protein" in MCE Product Catalog:

39
39 Publications Verification
Cat. No.: HY-19545A
CAS No.: 125941-87-9
Synonyms: R-(+)-SCH-23390 hydrochloride
SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM .
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26
26 Cited Publications
Cat. No.: HY-N6785
CAS No.: 78111-17-8
Okadaic acid, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid induces tau phosphorylation .
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26
26 Cited Publications
Cat. No.: HY-N6785A
CAS No.: 209266-80-8
Target:  

Phosphatase Apoptosis

Research Areas:  

Neurological Disease Cancer

Okadaic acid sodium, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid (sodium) has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid sodium increases of phosphorylation of a number of proteins by inhibiting PP, and acts a tumor promoter. Okadaic acid sodium induces tau phosphorylation .
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26
26 Cited Publications
Cat. No.: HY-115760
CAS No.: 175522-42-6
Target:  

Phosphatase

Research Areas:  

Neurological Disease Cancer

Okadaic acid ammonium salt, a marine toxin, is an inhibitor of protein phosphatases (PP). Okadaic acid ammonium salt has a significantly higher affinity for PP2A (IC50=0.1-0.3 nM), and inhibits PP1 (IC50=15-50 nM), PP3 (IC50=3.7-4 nM), PP4 (IC50=0.1 nM), PP5 (IC50=3.5 nM), but does not inhibit PP2C. Okadaic acid ammonium salt increases of phosphorylation of a number of proteins by inhibiting PP, and acts as a tumor promoter. Okadaic acid ammonium salt induces tau phosphorylation .
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10
10 Cited Publications
Cat. No.: HY-P7022
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNA2; IFN-Alpha-2; Interferon Alpha 2; IFNA2B; IFN-AlphaA; LeIF A; IFNA; Interferon Alpha 2a; Alpha-2a Interferon; Interferon Alpha-A; Interferon Alpha 2b; Interferon 1AB4; Interferon Alpha A; IFNA2C; Interferon Alpha-2; IFNA2A
Species:  
Human
Source:  
E. coli
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8
8 Cited Publications
Cat. No.: HY-P7023
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNA2; IFN-Alpha-2; Interferon Alpha 2; IFNA2B; IFN-AlphaA; LeIF A; IFNA; Interferon Alpha 2a; Alpha-2a Interferon; Interferon Alpha-A; Interferon Alpha 2b; Interferon 1AB4; Interferon Alpha A; IFNA2C; Interferon Alpha-2; IFNA2A
Species:  
Human
Source:  
E. coli
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4
4 Cited Publications
Cat. No.: HY-P7239
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL8; Chemokine (C-C Motif) Ligand 8; Prev. SCYA8; Small-Inducible Cytokine A8; MCP-2; C-C Motif Chemokine 8; HC14; SCYA10; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 8 (Monocyte Chemotactic protein 2); MCP2; Monocyte Chemoattractant protein 2
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-N0247
CAS No.: 58558-08-0
Saikosaponin B1 is a bioactive constituent of Radix Bupleuri. Saikosaponin B1 is an agonist of the 5-HT2C receptor with an EC50 of 147.41 μM. Saikosaponin B1 inhibits the Hedgehog (Hh) signaling pathway by targeting the transmembrane protein SMO. Sailosaponin B1 can reduce liver fibrosis. Saikosaponin B1 has anti-cancer activities thus can be studies in research for cancers such as Medulloblastoma (MB) .
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2
2 Cited Publications
Cat. No.: HY-15565
CAS No.: 832714-46-2
Purity:  99.73%
Research Areas:  

Metabolic Disease

APD668 is a potent, selective and orally active agonist of G-protein coupled receptor GPR119, with EC50s of 2.7 nM and 33 nM for hGPR119 and rGPR119, respectively. APD668 shows no significant inhibition of any of the five major CYP isoforms with the exception of CYP2C9 (Ki=0.1 μM). APD668 can be used for the research of steatohepatitis and diabetes .
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2
2 Cited Publications
Cat. No.: HY-P7238
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL8; Chemokine (C-C Motif) Ligand 8; Prev. SCYA8; Small-Inducible Cytokine A8; MCP-2; C-C Motif Chemokine 8; HC14; SCYA10; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 8 (Monocyte Chemotactic protein 2); MCP2; Monocyte Chemoattractant protein 2
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P7760
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL24; CK-Beta-6; Prev. SCYA24; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 24; Eotaxin-2; Eosinophil Chemotactic protein 2; MPIF-2; Chemokine (C-C Motif) Ligand 24; MPIF2; Small-Inducible Cytokine A24; Myeloid Progenitor Inhibitory Factor 2; C
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P71340
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STUB1; CLL-Associated Antigen KW-8; STIP1 Homology And U-Box Containing protein 1; Antigen NY-CO-7; CHIP; STIP1 Homology And U-Box Containing protein 1, E3 Ubiquitin protein Ligase; SDCCAG7; Heat Shock protein A Binding protein 2 (C-Terminal); HSPABP2; STIP1 Homology And U Box-Containing protein 1; NY-CO-7; Serologically Defined Colon Cancer Antigen 7; UBOX1; RING-Type E3 Ubiquitin Transferase; Carboxy Terminus Of Hsp70-Interacting protein; SCAR16; RING-Type E3 Ubiquitin Transferase CHIP; SCA48; E3 Ubiquitin-protein Ligase CHIP
Species:  
Human
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P80385
Synonyms: C C chemokine receptor type 2 antibody; C C CKR 2 antibody; C-C chemokine receptor type 2 antibody; C-C CKR-2 antibody; CC chemokine receptor type 2 antibody; CC CKR 2 antibody; CC-CKR-2 antibody; CCCKR2 antibody; CCR 2 antibody; CCR-2 antibody; CCR1L antibody; CCR2 antibody; CCR2_HUMAN antibody; CCR2A antibody; CCR2B antibody; CCR5L antibody; CD192 antibody; CD192 antigen antibody; Chemokine C C motif receptor 2 antibody; Chemokine CC Motif Receptor 2 antibody; CKR 2 antibody; CKR2 antibody; CKR2A antibody; CKR2B antibody; CMKBR2 antibody; MCP 1 R antibody; MCP-1-R antibody; MCP1 RECEPTOR antibody; MCP1R antibody; Monocyte chemoattractant protein 1 receptor antibody; Monocyte Chemotactic protein 1 Receptor antibody; Monocyte Chemotactic protein 1 Receptor antibody

Host:  

Rabbit

Application:  

WB, IHC-P, IP, FC

Reactivity:  

Human, Mouse

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2
2 Cited Publications
Cat. No.: HY-P7544
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IFNA2; IFN-Alpha-2; Interferon Alpha 2; IFNA2B; IFN-AlphaA; LeIF A; IFNA; Interferon Alpha 2a; Alpha-2a Interferon; Interferon Alpha-A; Interferon Alpha 2b; Interferon 1AB4; Interferon Alpha A; IFNA2C; Interferon Alpha-2; IFNA2A
Species:  
Mouse
Source:  
E. coli
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2
2 Cited Publications
Cat. No.: HY-P73094
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB2; P185erbB2; Prev. NGL; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2 (Neuro/Glioblastoma Derived Oncogene Homolog); HER2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2 Isoform C; Receptor Tyrosine-protein Kinase ErbB-2; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Proto-Oncogene C-ErbB-2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Proto-Oncogene Neu; Receptor Tyrosine-protein Kinase ErbB-2 Variant; P185(ErbB2); Truncated HER2 Splice Variant P100; C-ERB-2; Receptor protein-Tyrosine Kinase; C-ERB2; Metastatic Lymph Node Gene 19; MLN-19; Alternative protein ERBB2; HER-2; C-Erb B2/Neu protein; CD340; CD340 Antigen; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; HER-2/Neu; Tyrosine Kinase-Type Cell Surface Receptor HER2; Herstatin; Neuro/Glioblastoma Derived Oncogene Homolog; VSCN2; Human Epidermal Growth Factor Receptor 2; MLN19; Metastatic Lymph Node Gene 19 protein; TKR1; Erb-B2 Receptor Tyrosine Kinase 2; MLN 19
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P71666
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GUCY2C; Heat-Stable Enterotoxin Receptor; Prev. GUC2C; Guanylate Cyclase 2C (Heat Stable Enterotoxin Receptor); STAR; Heat Stable Enterotoxin Receptor; GC-C; Alternative protein GUCY2C; Guanylyl Cyclase C; DIAR6; STA Receptor; MECIL; HSER; MUCIL; GCC; HST
Species:  
Rat
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P75979
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPM1A; protein Phosphatase 1A (Formerly 2C), Magnesium-Dependent, Alpha Isoform; protein Phosphatase, Mg2+/Mn2+ Dependent 1A; protein Phosphatase, Mg2+/Mn2+ Dependent, 1A; protein Phosphatase 1A; protein Phosphatase 2C, Alpha Isoform; PP2Calpha; Alternati
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Cat. No.: HY-P700797
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KLRC2; NK Cell Receptor C; Killer Cell Lectin Like Receptor C2; NKG2-C; NKG2-C Type II Integral Membrane protein; CD159c; NKG2C; Killer Cell Lectin-Like Receptor Subfamily C, Member 2; CD159 Antigen-Like Family Member C; Natural Killer Cell Receptor G2-C
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P81053
Synonyms: Microtubule associated protein 2; MAP2A; MAP2B; MAP2C

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-13756S
CAS No.: 1356841-89-8
Purity:  98.36%
Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2
Tacrolimus- 13C,d2 (FK506- 13C,d2) is the 13C, deuterated-labeled Tacrolimus (HY-13756). Tacrolimus (FK506), a molecular glue, a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties .
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