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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
610 Results for "
3S
" in MedChemExpress (MCE) Product Catalog:
Products (610)
610 Results for "3S" in MCE Product Catalog:
601
601 Publications Verification
Synonyms: (1S,3R)-RSL3
Research Areas:
RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
37
37 Cited Publications
Research Areas:
iFSP1 is a potent, selective and glutathione-independent inhibitor of ferroptosis suppressor protein 1 (FSP1) (AIFM2) with an EC50 of 103 nM. iFSP1 selectively induces ferroptosis in GPX4-knockout cells which overexpressed FSP1. iFSP1 is able to sensitize a variety of human cancer cell lines to the ferroptosis inducer, such as (1S,3R)-RSL3 (HY-100218A) .
9
Category:
Cardiovascular Disease Flavonoids Flavones Phenols Polyphenols Plants Other Families Extract Disease Research Fields
Target:
9
9 Cited Publications
Synonyms: (S)-2-Amino-3-phenylpropionic acid
5
5 Cited Publications
Target:
Research Areas:
CYM5442 is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 can easily penetrate the central nervous system (CNS) .
5
5 Cited Publications
Cat. No.: HY-10968A
CAS No.: 1783987-80-3
Target:
Research Areas:
CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS) .
4
Target:
Research Areas:
CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors .
3
3 Cited Publications
Target:
Research Areas:
(1R,3R)-RSL3 is an isomer of RSL3 (HY-100218A). RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells .
2
2 Cited Publications
Cat. No.: HY-B0617S
CAS No.: 68684-40-2
Synonyms: S-Adenosyl methionine-d3; Ademetionine-d3; AdoMet-d3
2
2 Cited Publications
Cat. No.: HY-N0650S8
CAS No.: 105591-10-4
Synonyms: (-)-Serine-d3; (S)-Serine-d3
2
2 Cited Publications
Cat. No.: HY-W050031
CAS No.: 6168-83-8
Synonyms: (S)-β-Hydroxybutanoic acid; L-(+)-3-Hydroxybutyric acid; L-β-Hydroxybutyric acid
Category:
Microorganisms Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
Target:
2
2 Cited Publications
Cat. No.: HY-W050031A
CAS No.: 127604-16-4
Synonyms: (S)-β-Hydroxybutanoic acid sodium; L-(+)-3-Hydroxybutyric acid sodium; L-β-Hydroxybutyric acid sodium; Sodium (S)-3-hydroxybutanoate
Target:
Research Areas:
(S)-3-Hydroxybutanoic acid sodium ((S)-β-Hydroxybutanoic acid sodium) is a metabolite and a disease marker of depression. 3-Hydroxybutyric acid sodium is synthesized in the liver from acetyl-CoA, and can be used as an energy source by the brain when blood glucose is low.
2
2 Cited Publications
Synonyms: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
Category:
Microorganisms Neurological Disease Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics Cancer
Target:
2
2 Cited Publications
Target:
Research Areas:
CYM-5520 is a selective and allosteric sphingosine 1-phosphate receptor 2 (S1PR2) agonist with an EC50 of 480 nM. CYM-5520 does not activate S1PR1, S1PR3, S1PR4 and S1PR5 receptors. CYM-5520 can co-bind in the S1PR2 receptor with S1P. CYM-5520 can be used for osteoporosis research .
2
2 Cited Publications
Cat. No.: HY-N0215S10
CAS No.: 439685-11-7
Synonyms: (S)-2-Amino-3-phenylpropionic acid-13C9
1
1 Cited Publications
Cat. No.: HY-W747072
CAS No.: 71781-33-4
Synonyms: 3-Sulfocholyl Taurine; TCA3S
Target:
Research Areas:
3-Sulfo-taurocholic Acid Disodium Salt (3-Sulfocholyl Taurine; TCA3S) is a metabolite of the conjugated bile acid taurocholic acid. Plasma levels of 3-Sulfo-taurocholic Acid Disodium Salt are elevated in wild-type and Sortilin 1 (Sort1) knockout mice at 6 hours following bile duct ligation (BDL) and are further elevated in Sort1 knockout mice at 24 hours post-BDL.
1
1 Cited Publications
Synonyms: (2S)-α-Ethylglutamic acid; (2S)-α-EGLU
Target:
Research Areas:
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent .
1
1 Cited Publications
Cat. No.: HY-P70817
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGFR3; Mutant Fibroblast Growth Factor Receptor 3; Prev. ACH; Fibroblast Growth Factor Receptor 3-S; JTK4; Fibroblast Growth Factor Receptor; CD333; Receptor Protein-Tyrosine Kinase; CEK2; Hydroxyaryl-Protein Kinase; FGFR-3; Tyrosine Kinase JTK4; Fibrobla
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-Y1069S
CAS No.: 59652-74-3
Synonyms: (S)-Hydroxybutanedioic acid-d3; (S)-E 296-d3; L-Malic acid-d3
1
1 Cited Publications
Cat. No.: HY-N0650S
CAS No.: 201595-68-8
Synonyms: (-)-Serine-13C3; (S)-Serine-13C3
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
