4,4-dimethylcyclohexanone | MedChemExpress (MCE) Life Science Reagents

Research Areas:

Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC₅₀ of 0.94 nM. Cyclo(-RGDfK) potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

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35

Cyclo(-RGDfK) TFA

35 Publications Verification

Cat. No.: HY-P0023A

CAS No.: 500577-51-5

Target:

Research Areas:

Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the α_vβ₃ integrin, with an IC₅₀ of 0.94 nM . Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface .

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17

Alisporivir

17 Cited Publications

Cat. No.: HY-12559

CAS No.: 254435-95-5

Purity: 98.08%

Synonyms: Debio-025; DEB-025

Target:

Cyclophilin HCV

Research Areas:

HCV Bacterial Antibiotic Reactive Oxygen Species (ROS)

Alisporivir (Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.

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8

Cyclo(Phe-Pro)

8 Cited Publications

Cat. No.: HY-P1934

CAS No.: 14705-60-3

Synonyms: Cyclo(phenylalanylprolyl); A-64863

Target:

Research Areas:

Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) is a quorum-sensing molecule of Vibrio vulnificus that specifically interacts with RIG-I, inhibiting RIG-I polyubiquitination, suppressing IRF-3 activation, and reducing type I interferon production. Cyclo(Phe-Pro) enhances susceptibility to HCV and influenza virus and also alleviates plant aluminum toxicity stress. The mechanism of Cyclo(Phe-Pro) involves the regulation of host immune signaling pathways, bacterial virulence gene expression, and plant antioxidant systems, making it a promising candidate for research in viral infections, bacterial virulence regulation, and agricultural stress resistance .

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4

Cyclo(RGDyK)

4 Cited Publications

Cat. No.: HY-100563A

CAS No.: 217099-14-4

Purity: 99.83%

Target:

Research Areas:

Cyclo(RGDyK) is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

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4

Cyclo(RGDyK) trifluoroacetate

4 Cited Publications

Cat. No.: HY-100563

CAS No.: 250612-42-1

Purity: 99.92%

Target:

Research Areas:

Cyclo(RGDyK) trifluoroacetate is a potent and selective α_Vβ₃ integrin inhibitor with an IC₅₀ of 20 nM.

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4

BQ-123

4 Cited Publications

Cat. No.: HY-12378

CAS No.: 136553-81-6

Purity: 99.82%

Target:

Endothelin Receptor

Research Areas:

Cardiovascular Disease

BQ-123 is a potent and selective endothelin A (ETA) receptor antagonist with an IC₅₀ of 7.3 nM and a K_i of 25 nM. BQ-123 inhibits endothelin-1-mediated proliferation of human pulmonary artery smooth muscle cells and lowers blood pressure in different rat models of hypertension .

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4

Murepavadin TFA

4 Cited Publications

Cat. No.: HY-P1674A

CAS No.: 3053070-05-3

Synonyms: POL7080 TFA

Target:

Bacterial Antibiotic

Research Areas:

Reactive Oxygen Species (ROS)

Murepavadin (POL7080) (TFA), a 14-amino-acid cyclic peptide, is a highly potent, specific antibiotic. Murepavadin exhibits a potent antimicrobial activity for P. aeruginosa with MIC₅₀ and MIC₉₀ values both of 0.12 mg/L. Murepavadin also can target the lipopolysaccharide transport portin D. Murepavadin can be used for the research of bacterial resistance .

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3

Astressin

3 Cited Publications

Cat. No.: HY-P0257

CAS No.: 170809-51-5

Target:

CRFR

Research Areas:

Neurological Disease

Astressin is a potent corticotropin releasing factor (CRF) antagonist.

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2

Glutathione ethyl ester

2 Cited Publications

Cat. No.: HY-134124

CAS No.: 92614-59-0

Purity: 95.8%

Target:

Research Areas:

Metabolic Disease

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the in vitro production of embryos by enhancement of the antioxidative defense .

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2

Cyclo(Arg-Gly-Asp-D-Phe-Cys)

2 Cited Publications

Cat. No.: HY-P2300

CAS No.: 862772-11-0

Synonyms: Cyclo(RGDfC)

Target:

Research Areas:

Antibiotic Bacterial Na+/K+ ATPase

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors .

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2

Gramicidin S

2 Cited Publications

Cat. No.: HY-P5712

CAS No.: 113-73-5

Synonyms: Gramicidin soviet

Target:

Research Areas: