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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
4-HBA
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "4-HBA" in MCE Product Catalog:
Cat. No.: HY-CE00345
CAS No.: 27718-41-8
Synonyms: Coenzyme A,S-(4-hydroxybenzoate); 4-Hydroxybenzoyl-CoA; 4-Hydroxybenzoyl-coenzyme A
Target:
Research Areas:
(4-Hydroxybenzoyl)-CoA (Coenzyme A,S-(4-hydroxybenzoate)) is the S-(4-hydroxybenzoyl) derivative of coenzyme A. 4-Hydroxybenzoyl-CoA binds to the thioesterase active site and is hydrolyzed to CoA and 4-HBA. 4-Hydroxybenzoyl-CoA is the natural substrate of 4-Hydroxybenzoyl-CoA thioesterase and is also the dehalogenase product bound at its active site in the crystal structure [4] .
Cat. No.: HY-L0124V
13,082 compounds
The basic requirements for the compounds that are supposed to penetrate the blood-brain barrier are somewhat different from those for the majority of drug discovery projects. Alongside the known problem with delivery of the large and non-polar compounds and their penetrability through the cell membrane, the other issue arises as well: small and polar compounds are not able to pass the Blood-Brain Barrier. Chemspace CNS-focused library comprises quite small, non-polar compounds that are also free from PAINS/toxic fragments and aggregators.
Cat. No.: HY-L0093V
10,119 compounds
Diversity-based screening continues to be a vital tool for drug discovery. Efficiency and productivity can be improved by using screening libraries that offer maximum diversity whilst retaining drug-like properties. Chemspace Scaffold derived set composes 10,119 compounds, which including 3,373 scaffolds, 3 compounds per each. This library has exceptional coverage of drug-like chemical space.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
