10 Results for "

5-HT2BR

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "5-HT2BR" in MCE Product Catalog:

PRX-08066
PRX-08066
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Cat. No.: HY-15472
CAS No.: 866206-54-4
Purity:  97.46%
Target:  

5-HT Receptor p38 MAPK TGF-β Receptor FGFR Apoptosis Caspase

Research Areas:  

Cardiovascular Disease Neurological Disease Cancer

PRX-08066 is a selective and orally active 5-hydroxytryptamine receptor 2B (5-HT2BR) antagonist with a Ki of 3.4 nM. PRX-08066 inhibits the MAPK pathway, 5-HT release and fibrotic factor (TGFβ1, CTGF and FGF2) expression. PRX-08066 inhibits the proliferation of KRJ-I cells and induces apoptosis (caspase-3 activation). PRX-08066 inhibits pulmonary vascular remodeling. PRX-08066 can be used of pulmonary Arterial Hypertension (PAH) and neuroendocrine tumor (NET) .
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Paynantheine
Paynantheine
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Cat. No.: HY-124412
CAS No.: 4697-66-9
Category:  

Alkaloids Quinolizidine Alkaloids 500 - Internal Server Error | MedChemExpress

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