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235 Results for "

5-HT2c

" in MedChemExpress (MCE) Product Catalog:

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SCH-23390 hydrochloride

39 Publications Verification

Cat. No.: HY-19545A

CAS No.: 125941-87-9

Synonyms: R-(+)-SCH-23390 hydrochloride

Target:

Dopamine Receptor 5-HT Receptor Potassium Channel

Research Areas:

Neurological Disease

SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D₁-like receptor antagonist with K_is of 0.2 nM and 0.3 nM for the D₁ and D₅ receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT_2C receptor agonist with a K_i of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT₂ and 5-HT_1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC₅₀ of 268 nM .

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