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276 Results for "

5R

" in MedChemExpress (MCE) Product Catalog:

Products (276)

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SHU 9119

3 Cited Publications

Cat. No.: HY-P0227

CAS No.: 168482-23-3

Target:

Melanocortin Receptor

Research Areas:

Metabolic Disease

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC₅₀ values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

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YM-90709

1 Cited Publications

Cat. No.: HY-19969

CAS No.: 163769-88-8

Target:

Interleukin Related

Research Areas:

Inflammation/Immunology

YM-90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).YM-90709 potently inhibits the binding of [ ¹²⁵I]-IL-5 to IL-5R on human peripheral eosinophils and eosinophilic HL-60 clone 15 cells with IC₅₀ values of 1.0 and 0.57 μM .

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Benralizumab

1 Cited Publications

Cat. No.: HY-P9923

CAS No.: 1044511-01-4

Synonyms: MEDI-563; BIW-8405; KHK4563

Target:

Interleukin Related Apoptosis

Research Areas:

Inflammation/Immunology Cancer

Benralizumab (MEDI-563) is an interleukin-5 receptor α (IL-5Rα)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma .

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D-Mannosamine hydrochloride

1 Cited Publications

Cat. No.: HY-W021425

CAS No.: 5505-63-5

Synonyms: (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride

Category:

Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides

Target:

Drug Derivative

D-Mannosamine ((2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors .

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5-R-Rivaroxaban

1 Cited Publications

Cat. No.: HY-76948

CAS No.: 865479-71-6

Target:

Factor Xa

Research Areas:

Cardiovascular Disease

5-R-Rivaroxaban is (R)-enantiomer of Rivaroxaban. Rivaroxaban (BAY 59-7939) is a highly potent and selective, direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC₅₀ 0.7 nM; K_i 0.4 nM).

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